Leukemia is a cancer of the blood cells. Most blood cells form in the bone marrow. In leukemia, cancerous blood cells form and crowd out the healthy blood cells in the bone marrow. The type of leukemia depends on the type of blood cell that has become cancerous.
Chronic Lymphocytic Leukaemia treatment in India
Chronic lymphocytic leukemia (also called CLL) – Chronic lymphocytic leukemia (also called CLL) is a blood and bone marrow disease that usually gets worse slowly. Like all leukemia, chronic lymphocytic leukemia is a cancer of the blood cells. Chronic lymphocytic leukemia (CLL) affects a certain type of white blood cell, called a B lymphocyte. This disease is also called B-cell chronic lymphocytic leukemia. B cells originate in the bone marrow, mature in the lymph nodes, and then circulate in the blood to help fight infections. Chronic lymphocytic leukemia (CLL) is the second most common type of leukemia in adults.
Chronic lymphocytic leukemia ( CLL ) treatment in India:
Bone Marrow or Cord Blood Transplant in India –The type of bone marrow or cord blood transplant that is most often used to treat Chronic lymphocytic leukemia (CLL) is called an allogeneic transplant. An allogeneic transplant replaces the abnormal cells in the patient’s bone marrow with healthy blood-forming cells from a family member, unrelated donor, or cord blood unit. The first step in an allogeneic transplant is finding a matching donor – someone who can donate marrow or peripheral blood – or a cord blood unit to provide these blood-forming cells.
Reduced-Intensity and Non-Myeloablative Transplants in India –For some people with chronic lymphocytic leukemia or CLL, an allogeneic transplant may offer the best chance for long-term remission. In a standard transplant, patients get very high doses of chemotherapy and/or radiation before the transplant. This is called the pre-transplant conditioning regimen. A high-dose conditioning regimen has two goals:
Autologous Transplants for CLL in India-Autologous transplantation is not as common as allogenic transplantation in treating Chronic lymphocytic leukemia (CLL). In an autologous transplant, a patient receives his or her own blood-forming cells. These cells are collected from the patient’s blood or marrow, preferably when he or she is in remission, and then frozen and stored. The patient then receives a very high-dose conditioning regimen, after which the thawed cells are given back to the patient intravenously. Autologous transplant recipients have been shown to experience remissions of 5-6 years, so it remains a possible treatment option for some patients with CLL.
Chemotherapy for Leukemia in India -During chemotherapy, you’ll be given potent drugs that must be toxic enough to damage or kill leukemic cells. At the same time, they take aim at normal cells and can cause side effects. Yet, not everyone experiences side effects and people react differently. Doctors commonly combine two or more chemotherapy drugs to treat CLL. Each drug type works in a different way to kill the cancerous cells. Combining drug types can strengthen their effectiveness.
Monoclonal Antibody Therapy in India for Blood Cancers – Drug therapy using monoclonal antibodies can be an effective treatment. A monoclonal antibody is an immune protein made in a laboratory. It’s designed to target a specific molecule on the surface of CLL cells. The monoclonal antibody aims for the molecule and attaches itself to the cell, causing the cell to die. Monoclonal antibody therapies can cause side effects, but they’re generally milder than chemotherapy’s side effects. Because they’re designed to target and attack specific substances, they tend to leave normal cells unharmed.
Eosinophilic Leukemia treatment in India
Eosinophilic leukemia is a disorder in which too many white blood cells, known as Eosinophils, are produced in the blood, bone marrow, and other tissues of the body. Ordinarily, these white blood cells help the body fight diseases and infections. With Eosinophilic leukemia, the overabundance of white blood cells can sometimes lead to dangerous results.
Treatments forEosinophilic leukemia in India.
Chemotherapy for the treatment of Eosinophilic leukemia– Chemotherapy is the use of drugs to kill cancer cells, usually by stopping the cancer cells’ ability to grow and divide. Systemic chemotherapy is delivered through the bloodstream to reach cancer cells throughout the body. Chemotherapy is given by a medical oncologist, a doctor who specializes in treating cancer with medication, or a hematologist, a doctor who specializes in treating blood disorders. A chemotherapy regimen (schedule) usually consists of a specific number of cycles given over a set period of time. A patient may receive one drug at a time or a combination of different drugs at the same time.
Surgery for the treatment of Eosinophilic leukemia – Surgery to remove the spleen (called a splenectomy), which also makes white blood cells, may be recommended for some patients. A surgical oncologist is a doctor who specializes in treating cancer using surgery.
Immunotherapy for the treatment of Eosinophilic leukemia – Immunotherapy (also called biologic therapy), is designed to boost the body’s natural defenses to fight cancer. It uses materials made either by the body or in a laboratory to bolster, target, or restore immune system function. Recombinant interferon-alpha (Alferon, Roferon-A, Intron A) is a biologic therapy that is occasionally used to treat Eosinophilic Leukemia.
Targeted Therapy for the treatment ofEosinophilic leukemia Targeted therapy is a treatment that targets cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. This type of treatment blocks the growth and spread of cancer cells while limiting damage to normal cells.
Stem Cell Transplantation for Treatment of Eosinophilic leukemia A stem cell transplant is a medical procedure in which diseased bone marrow is replaced by highly specialized cells, called hematopoietic stem cells. Hematopoietic stem cells are found both in the bloodstream and in the bone marrow. Today, this procedure is more commonly called a stem cell transplant, rather than bone marrow transplant, because it is the blood stem cells that are typically being transplanted, not the actual bone marrow tissue. Before recommending transplantation, doctors will talk with the patient about the risks of this treatment and consider several other factors, such as the type of cancer, results of any previous treatment, and the patient’s age and general health.
Radiation Therapy for the treatment of Eosinophilic leukemia Radiation therapy is the use of high-energy x-rays or other particles to kill cancer cells. A doctor who specializes in giving radiation therapy to treat cancer is called a radiation oncologist. The most common type of radiation therapy is called external-beam radiation therapy, which is radiation given from a machine outside the body. When radiation therapy is given using implants, it is called internal radiation therapy or brachytherapy. A radiation therapy regimen (schedule) usually consists of a specific number of treatments given over a set period of time. Side effects from radiation therapy include fatigue, mild skin reactions, upset stomach, and loose bowel movements. Most side effects go away soon after treatment is finished.
T-Cell Leukaemia treatment in India
What is T- Cell?
A T-cell is a type of white blood cell that directly helps the body’s immune system fight infection. T-Cell Leukemia -T-cell leukemia/lymphoma (ATL) is a rare cancer of the immune system’s own T-cells.
Types of ATL
Large Granular Lymphocytic Leukemia(LGLL) -LGLL is slow-growing T-cell leukemia and is more common in women than in men. The cause of Large granular lymphocytic leukemia or LGLL is unknown, although about 30% of people with LGLL also have rheumatoid arthritis (a chronic disease causing swelling in the joints of the hands, feet, wrists, knees, hips, or shoulders).
T-Cell Prolymphocytic Leukemia (T-PLL) T-cell prolymphocytic leukemia or T-PLL is an aggressive subtype of CLL. It is more common in older men, but women may also develop T-cell prolymphocytic leukemia. It can affect the skin but in a different way.
Adult T-Cell Leukemia/Lymphoma (ATLL) -Adult T-cell leukemia/lymphoma or ATLL has four subtypes. Depending on the different features, it is subclassified as smoldering, chronic, acute, or adult T-cell lymphoma (cancer of the lymph system). The acute and adult T-cell lymphoma subtypes grow quickly. ATLL is caused by a retrovirus called the human T-cell leukemia virus (HTLV1).
Sezary Syndrome -Sezary syndrome is a form of mycosis fungoides, T-cell lymphoma that occurs in the skin. Sezary syndrome is usually slow-growing and takes years to develop from mycosis fungoides, which is located only on the skin. Sezary syndrome is generally diagnosed when large numbers of lymphoma cells are found in the blood, often together with reddening of the skin.
Treatments for T Cell Blood Cancer In India-
Chemotherapy Treatment in India –Chemotherapy is the use of drugs to kill cancer cells, usually by stopping the cancer cells’ ability to grow and divide. Systemic chemotherapy is delivered through the bloodstream to reach cancer cells throughout the body. Chemotherapy is given by a medical oncologist, a doctor who specializes in treating cancer with medication, or a hematologist, a doctor who specializes in treating blood disorders. A chemotherapy regimen (schedule) usually consists of a specific number of cycles given over a set period of time. A patient may receive one drug at a time or a combination of different drugs at the same time.
Immunotherapy Treatment in India -Immunotherapy (also called biologic therapy) is designed to boost the body’s natural defenses to fight cancer. It uses materials made either by the body or in a laboratory to bolster, target, or restore immune system function. Recombinant interferon-alpha (Alferon, Roferon-A, Intron A) is used as a treatment for ATLL. Interferon is a natural protein found in the body that stimulates the immune system. Learn more about immunotherapy.
Targeted Therapy Treatment in India for Blood Cancer -Targeted therapy is a treatment that targets the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. This type of treatment blocks the growth and spread of cancer cells while limiting damage to normal cells.
Stem Cell Transplant treatment for Blood Cancer / Bone Marrow Transplant Treatment in India –A stem cell transplant is a medical procedure in which diseased bone marrow is replaced by highly specialized cells, called hematopoietic stem cells. Hematopoietic stem cells are found both in the bloodstream and in the bone marrow. Today, this procedure is more commonly called a stem cell transplant, rather than a bone marrow transplant, because it is the blood stem cells that are typically being transplanted, not the actual bone marrow tissue.
