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Keratininzing Epidermoid Carcinoma conjunctiva treatment in india

Clinical Case Report: Multimodal Management of Keratinizing Epidermoid Carcinoma (Squamous Cell Carcinoma) of the Eye via Surgical Resection, or Chemotherapy / Targeted Therapy / Immunotherapy in a 65 Year Old Patient from Uganda

As per the shared reports, the patient has been diagnosed with Keratinizing Epidermoid Carcinoma involving the Conjunctiva.

Keratinizing Epidermoid Carcinoma (also known as squamous cell carcinoma) involving the conjunctiva is the most frequent malignant tumor of the ocular surface, arising from the squamous epithelial cells of the conjunctiva.

The conjunctiva is a thin, transparent mucous membrane that lines the inner eyelids and covers the white part of the eyeball (sclera), extending to the edge of the cornea. We will need to perform some investigations upon patient arrival to confirm the diagnosis.

Investigations required: The patient would require a detailed physical and clinical examination which includes imaging tests like MRI, PET CT, Biopsy, blood tests, molecular study and NGS study and other routine investigations.

Treatment plan: The final treatment plan will be decided only after the outcome of complete investigations and reviewing the patient in person.

If the disease is localized, she will need surgery.

If the disease is advanced and has metastasized, patient will need chemotherapy with target therapy or immunotherapy.

Depending upon investigative outcomes of the molecular study and NGS study, if any mutation is detected, the doctors will add Targeted therapy. If the mutation is not detected, the doctors may need to add Immunotherapy.

Surgery for Epidermoid tumor of eye involves surgical excision to remove the tumor, including its capsule to prevent recurrence this may involve an incision in the eyebrow to approach the tumor or an orbital approach depending upon tumor size and location.

Chemotherapy is a type of cancer treatment that uses one or more anti-cancer drugs as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent, or it may aim to prolong life or to reduce symptoms.

Targeted therapy is a cancer treatment that uses drugs to target specific molecules on cancer cells. These molecules control how cancer cells grow, divide, and spread. 

Immunotherapy is a treatment that uses the body’s immune system to fight cancer, infections, and other diseases. It can also be used to treat allergies.

The cycles of Chemotherapy will run once every 2 weeks. Thus, it may take between 12-15 weeks to finish the treatment.

Kindly Note: The advised plan is solely based on the reports shared with us. The final line of treatment will be decided post the physical and clinical evaluations of the patient on arrival only.

We would recommend the following hospitals having Top doctors as below: 

1. Amrita Hospitals // Dr. Vidit Kapoor // Dr. Abhishek Agarwal

2. Sharda University Hospital // Dr. Anil Thakwan // Dr. Hemkant Verma

3. Artemis Hospital // Dr. Mukesh Patekar // Dr. Tapan Singh Chauhan 

4. Sarvodaya Healthcare // Dr. Dinesh Pendharkar // Dr. Naveen Sanchety

Estimated costs:

Estimated cost of Initial Evaluations will be approx. USD 1000-1200 on OPD basis. 

The Estimated cost of Surgery at the various hospital will be approx.: 

HospitalsCityEstimated cost of Surgery
Amrita Hospitals Faridabad (DELHI NCR)USD 5000 – USD 6000
Sharda University HospitalNoida (DELHI NCR)USD 4000 – USD 5000
Sarvodaya Hospital Faridabad (Delhi-NCR) USD 4500 – USD 5500
Artemis Hospital Gurgaon (DELHI NCR)USD 6000- USD 7000

**If the viral (HIV) load is high the cost may go up by $1000 in surgery.

The Estimated cost of Chemotherapy with Targeted Therapy per cycle (Daycare basis) at the various hospital will be approx.: She may need 5-6 cycles of chemo.

HospitalsCityEstimated cost of Chemotherapy with Targeted Therapy per cycle
Amrita Hospitals Faridabad (DELHI NCR)USD 3000-3500
Sharda University HospitalNoida (DELHI NCR)USD 2700-3200
Sarvodaya Hospital Faridabad (Delhi-NCR) USD 2900- 3300
Artemis Hospital Gurgaon (DELHI NCR)USD 3000- 3800

**Chemotherapy with immunotherapy will also cost almost the same.

Kindly Note: The given cost is a tentative cost based on the shared information. If the investigations shed a new picture, the cost may vary accordingly.

Stay in India – The patient will require 3-5 days for initial evaluations on an OPD basis.

If chemotherapy is needed the patient will require chemotherapy on daycare basis. It may take 15-18 weeks to complete the chemotherapy.

If only surgery is needed the patient may need 5-7 days in the hospital. She may need 2-3 weeks of follow up in India.

Total stay in India – The total stay will depend upon the procedure. But he may plan minimum 1 month and maximum 2-3 months of stay in India.

Inclusions:

  1. The cost of all investigations related to the treatment.
  2. The cost of treatment – Surgery / Chemo
  3. The doctor’s fee, Charges etc.
  4. The cost of chemo is for day care admission in case of chemo.
  5. The cost of admission in the hospital for up to 7 days in case of HIPEC.
  6. Medical Consumables and Medicines towards the treatment. 
  7. All meals in case of surgical admission.
  8. It also includes complementary Airport Transfers, Forex Services and assistance.

Exclusions:

1. Any consultation other than in discussion
2. Extended stay
3. Treatment for any other illness

On Arrival:

The patient and his attendants will be received at the airport by our Representative. Apart from the medical and nursing team, one Case Manager will take care of all the needs. We shall also assist them with the reasonably charged accommodation near the hospital.  Patient and attendant may arrange 35-50 USD per day toward accommodation and food at Guest House.

Hope I have been able to give you a satisfactory answer to the query. Do kindly ask for any clarifications needed. I will be happy to answer & shall look forward to assisting you.

Aabbhik Moitra

CTA Doctor

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