<\/span><\/h3>\n\n\n\n\u25cf Bone marrow harvest – <\/strong>Which is a mini surgical procedure, one under general anesthesia, in which the donor will be asleep and bone marrow removed from the back of hip bones. The amount of bone marrow removed depends on the weight and on the receiving patient.<\/p>\n\n\n\n\u25cf Leukapheresis – <\/strong>Firstly, some shots are given to the donor to help stem cells move to the bloodstream. Using a separation machine part of white blood cells that contains stem cells are separated and removed to be later given to the recipient. The red blood cells are returned to the donor.<\/p>\n\n\n\n<\/span>What is the procedure for Bone Marrow Transplant Surgery? <\/b><\/span><\/h3>\n\n\n\n1. Conditioning
\n2. Stem cell infusion
\n3. Neutropenic phase
\n4. Engraftment phase
\n5. Post- engraftment phase<\/p>\n\n\n\n
<\/span>1. Conditioning<\/b><\/span><\/h4>\n\n\n\nThe conditioning period last for 7-10 days
\nThe purpose is (by delivery of chemo and \/ or radiation therapy).
\n\u25cf To eliminate Malignancy
\n\u25cf To provide immune suppression to prevent rejection of new stem cell
\n\u25cf Create space for new cells<\/p>\n\n\n\n
<\/span>2. Stem cell processing and infusion<\/strong><\/span><\/h4>\n\n\n\n\u25cf Infusion \u2013 20 minutes to an hour, varies depending on the volume infused
\n\u25cf The stem cell may be processed before infusion if indicated
\n\u25cf Depletion of T-cells can be performed to decrease GVHD
\n\u25cf Infused through a CVL, much like a blood transfusion
\nAnaphylaxis, volume overload, and a (rare) transient GVHD are the major potential complications involved.
\nStem cell products that have been cryopreserved contain dimethyl sulfoxide as a preservative and potentially can cause renal failure, in addition to the unpleasant smell and taste.<\/p>\n\n\n\n
<\/span>3. Neutropenic phase<\/b><\/span><\/h4>\n\n\n\nDuring the period(2-4 weeks) , the patient essentially has no effective immune system Healing is poor and the patient is very susceptible to infection Supportive care and empiric antibiotic therapy are the mainstays of successful passage through this phase.<\/p>\n\n\n\n
<\/span>4. Engraftment phase<\/b><\/span><\/h4>\n\n\n\nDuring this period (several weeks), the healing process begins with resolution of mucosities and lesions required in addition fever begin to subside and infection often begin to clear. The greatest challenges at this time are management of GVHD and prevention of viral infections(Especially CMV)<\/p>\n\n\n\n
<\/span>5. Post – Engraftment phase<\/b><\/span><\/h4>\n\n\n\nThis period last for months to year hallmark of this phase includes the gradual development of tolerance weaning off of immunosuppression management of chronic GVHD and documentation of immune reconstition.<\/p>\n\n\n\n
<\/span>What are the Steps of Stem Cell Transplant Treatment in IndiA? <\/b><\/span><\/h3>\n\n\n\n<\/span>Before the Procedure<\/b><\/span><\/h5>\n\n\n\nBefore treatment begins, the patient will need to undergo some clinical and physical investigation to proceed with further treatment plans. Central venous catheters tubes (1 or 2) inserted into the bloodstream in the neck region or arm. These tubes provide treatment, fluids, and nutrients if needed. It is also used to pull out blood. The patient can talk to a doctor or a provider for counseling if needed, which will help to prepare for the treatment of bone marrow transplants.
\nThe patient will need to plan out for the procedure and need to handle tasks that are required after transplant:<\/p>\n\n\n\n
\u25cf Arrange medical leave from office work
\n\u25cf Complete an advance care directive
\n\u25cf Take care of some of the financial statements
\n\u25cf Arrange care of yourself.
\n\u25cf Arrange someone for helping with household chores
\n\u25cf Confirming the health insurance coverage
\n\u25cf Bill payments
\n\u25cf Arrange someone for the care of your children.
\n\u25cf Find a house or home nearby the hospital, if needed.<\/p>\n\n\n\n
<\/span>After the Procedure <\/b><\/span><\/h5>\n\n\n\nBone marrow transplant procedure is done in patients or in hospitals or medical centres which are specialized in BMT. To avoid any kind of infection, patient will be in the hospital for the treatment. Stay in hospital will depends on if the patient suddenly faces any health complications related to bone marrow transplant, transplant type.<\/p>\n\n\n\n
<\/span>When a patient is in hospital:<\/b><\/span><\/h3>\n\n\n\n\u25cf The doctor\u2019s team will regularly monitor patient\u2019s blood count and vital signs.
\n\u25cf You will take precautionary medications to prevent GVHD, to treat or prevent infections; which includes antibiotics, antifungals, and antiviral medicines.
\n\u25cf Blood transfusion will be needed depending upon the severity of the disease.
\n\u25cf All food nutrition\u2019s will be fed through IV.
\n\u25cf Before discharge make sure of all instructions and care which should get follow after discharge.<\/p>\n\n\n\n
<\/span>What is the potential risk when stem cells come from donors?<\/b><\/span><\/h3>\n\n\n\nIf you receive a transplant that uses stem cells from a donor (allogeneic transplant), you may be at risk of developing graft-versus-host disease (GVHD). This condition occurs when the donor stem cells that make up your new immune system see your body\u2019s tissues and organs as something foreign and attack them.
\nGVHD may happen at any time after your transplant. Many people who have an allogeneic transplant get GVHD at some point. The risk of GVHD is a bit greater if the stem cells come from an unrelated donor, but it can happen to anyone who gets a bone marrow transplant from a donor.<\/p>\n\n\n\n
There are two kinds of GVHD: acute and chronic. Acute GVHD usually happens earlier, during the first months after your transplant. It typically affects your skin, digestive tract or liver. Chronic GVHD typically develops later and can affect many organs.<\/p>\n\n\n\n
<\/span>What are the signs and symptoms of GVHD?<\/b><\/span><\/h3>\n\n\n\n\u25cf Rash
\n\u25cf Shortness of breath
\n\u25cf Joint or muscle pain
\n\u25cf Vision changes, such as dry eyes
\n\u25cf Persistent cough
\n\u25cf Dry mouth
\n\u25cf Skin changes, including scarring under the skin or skin stiffness
\n\u25cf Mouth sores
\n\u25cf Diarrhea
\n\u25cf Yellow tint to your skin or the whites of your eyes (jaundice)
\n\u25cf Nausea
\n\u25cf Vomiting<\/p>\n\n\n\n
<\/span>What you can expect in Stem Cell Transplant? <\/b><\/span><\/h3>\n\n\n\n<\/span>During your bone marrow transplant treatment –<\/strong><\/span><\/h5>\n\n\n\nOn the day of your transplant, stem cells are infused into the body through your central line. The infusion is painless. You\u2019ll be awake during the procedure. After the transplant new stem cells enter the body, they travel through the blood to your bone marrow. Cells multiply and begin to make new and healthy blood cells. This process is called engraftment. It takes some weeks before the number of blood cells in your body starts to return to normal. It will be longer periods for some patients.<\/p>\n\n\n\n
<\/span>After the transplant procedure-<\/strong><\/span><\/h5>\n\n\n\nIn india for bone marrow transplant, some tests are done to monitor the condition. Doctors may recommend some medications to manage complications, such as nausea and diarrhea.
After a bone marrow transplant, you will need to remain under close medical care. Any infections or complications, you may need to stay in the hospital for several days. Depending upon the type of transplant and the risk of complications, you\u2019ll need to remain near the hospital for several weeks to months to allow close monitoring.
You may also need periodic transfusions of red blood cells and platelets until your bone marrow begins producing enough of those cells on its own. <\/p>\n\n\n\n
<\/span>Do I have to take medications after the Bone Marrow Transplant? <\/b><\/span><\/h3>\n\n\n\nIf your bone marrow transplant is using stem cells from a donor (allogeneic transplant), your doctors may prescribe medications to help prevent graft-versus-host disease and reduce your immune system\u2019s reaction (immunosuppressive medications).
\nAfter your transplant, it takes time for your immune system to recover. During this time, you may be given medications to prevent infections.<\/p>\n\n\n\n
<\/span>What kind of Lifestyle and diet factors are important after the Stem Cell Transplant Procedure? <\/b><\/span><\/h3>\n\n\n\nAfter bone marrow transplant treatment or BMT, some diet factors need to change. You will need to add a healthy diet and nutrition\u2019s to meet needs. Dietician can also give you food suggestions to control side effects of chemotherapy and radiation, such as nausea.
\nSome of recommendations of food may include:
\n\u25cf Avoid or restrict alcohol intake
\n\u25cf Limits your salt intake.
\n\u25cf Eat a variety of protein rich food including vegetables, fruits, meats, fish, healthy fast, olive oil.
\n\u25cf Avoid grapefruit due to their effect on a group of immunosuppressive medications
\n\u25cf Avoid smoking<\/p>\n\n\n\n
<\/span>What are the results of bone marrow transplant treatment in India? <\/b><\/span><\/h3>\n\n\n\nBone marrow transplant treatment or BMT cures some diseases and puts others into remission.
\nGoals of bone marrow transplant treatment depends on individual situations. It improves quality of life.<\/p>\n\n\n\n
Some people complete bone marrow transplantation some people complete bone marrow transplantation with few side effects and complications. Others experience numerous challenging problems, both short and long term. The severity of side effects and the success of the transplant vary from person to person and sometimes can be difficult to predict before the transplant.<\/p>\n\n\n\n
It can be discouraging if significant challenges arise during the bone marrow transplant process. However, it is sometimes helpful to remember that many survivors also experienced some very difficult days during the transplant process but ultimately had successful transplants and have returned to normal activities with a good quality of life. If you want to know the bone marrow transplant price in India, particularly in cities like Delhi, Bangalore, and Mumbai, you\u2019re in the right place for bone marrow transplant costs. Our team can provide detailed pricing information and help guide you, so book Your free second opinion today.<\/p>\n\n\n\n
<\/span>Which are good hospitals for bone marrow transplant in India?<\/b><\/span><\/h3>\n\n\n